Phenotypic Alterations in Hippocampal NPY- and PV-Expressing Interneurons in a Presymptomatic Transgenic Mouse Model of Alzheimer’s Disease

Interneurons, key regulators of hippocampal neuronal network excitability and synchronization, are lost in advanced stages of Alzheimer’s disease (AD). Given that network changes occur at early (presymptomatic) stages, we explored whether alterations of interneurons also occur before amyloid-beta (A...

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Detalles Bibliográficos
Autores principales: Mahar, Ian, Albuquerque, Marilia Silva, Mondragon-Rodriguez, Siddhartha, Cavanagh, Chelsea, Davoli, Maria Antonietta, Chabot, Jean-Guy, Williams, Sylvain, Mechawar, Naguib, Quirion, Rémi, Krantic, Slavica
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5243860/
https://www.ncbi.nlm.nih.gov/pubmed/28154533
http://dx.doi.org/10.3389/fnagi.2016.00327

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5243860/
https://www.ncbi.nlm.nih.gov/pubmed/28154533
http://dx.doi.org/10.3389/fnagi.2016.00327

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