Generation of α-1,3-galactosyltransferase knocked-out transgenic cloned pigs with knocked-in five human genes

Recent progress in genetic manipulation of pigs designated for xenotransplantation ha6s shown considerable promise on xenograft survival in primates. However, genetic modification of multiple genes in donor pigs by knock-out and knock-in technologies, aiming to enhance immunological tolerance agains...

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Detalles Bibliográficos
Autores principales: Kwon, Dae-Jin, Kim, Dong-Hwan, Hwang, In-Sul, Kim, Dong-Ern, Kim, Hyung-Joo, Kim, Jang-Seong, Lee, Kichoon, Im, Gi-Sun, Lee, Jeong-Woong, Hwang, Seongsoo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2016
Materias:
Brief Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5243873/
https://www.ncbi.nlm.nih.gov/pubmed/27554374
http://dx.doi.org/10.1007/s11248-016-9979-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5243873/
https://www.ncbi.nlm.nih.gov/pubmed/27554374
http://dx.doi.org/10.1007/s11248-016-9979-8

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