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2-(2-(4-Benzoylpiperazin-1-yl)ethyl)isoindoline-1,3-dione derivatives: Synthesis, docking and acetylcholinesterase inhibitory evaluation as anti-alzheimer agents

OBJECTIVE(S): Alzheimer’s disease (AD) as progressive cognitive decline and the most common form of dementia is due to degeneration of the cholinergic neurons in the brain. Therefore, administration of the acetylcholinesterase (AChE) inhibitors such as donepezil is the first choice for treatment of...

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Detalles Bibliográficos
Autores principales: Mohammadi-Farani, Ahmad, Abdi, Nasibeh, Moradi, Alireza, Aliabadi, Alireza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mashhad University of Medical Sciences 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5243976/
https://www.ncbi.nlm.nih.gov/pubmed/28133526
http://dx.doi.org/10.22038/ijbms.2017.8095