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Cisplatin cytotoxicity is dependent on mitochondrial respiration in Saccharomyces cerevisiae
OBJECTIVE(S): To understand the role of mitochondrial respiration in cisplatin sensitivity, we have employed wild-type and mitochondrial DNA depleted Rho0 yeast cells. MATERIALS AND METHODS: Wild type and Rho0 yeast cultured in fermentable and non-fermentable sugar containing media, were studied for...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Mashhad University of Medical Sciences
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5243979/ https://www.ncbi.nlm.nih.gov/pubmed/28133529 http://dx.doi.org/10.22038/ijbms.2017.8099 |