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Tumour-derived alkaline phosphatase regulates tumour growth, epithelial plasticity and disease-free survival in metastatic prostate cancer

BACKGROUND: Recent evidence suggests that bone-related parameters are the main prognostic factors for overall survival in advanced prostate cancer (PCa), with elevated circulating levels of alkaline phosphatase (ALP) thought to reflect the dysregulated bone formation accompanying distant metastases....

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Detalles Bibliográficos
Autores principales: Rao, S R, Snaith, A E, Marino, D, Cheng, X, Lwin, S T, Orriss, I R, Hamdy, F C, Edwards, C M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5243990/
https://www.ncbi.nlm.nih.gov/pubmed/28006818
http://dx.doi.org/10.1038/bjc.2016.402