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Perivascular PDGFR-β is an independent marker for prognosis in renal cell carcinoma

BACKGROUND: Renal cell carcinoma (RCC) is a highly vascularised tumour, where anti-angiogenic treatment with multi-tyrosine-kinase-inhibitor, is used for first-line treatment of metastatic disease. Variations in vascular characteristics are likely to contribute to variations in intrinsic aggressiven...

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Detalles Bibliográficos
Autores principales: Frödin, Magnus, Mezheyeuski, Artur, Corvigno, Sara, Harmenberg, Ulrika, Sandström, Per, Egevad, Lars, Johansson, Martin, Östman, Arne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5243993/
https://www.ncbi.nlm.nih.gov/pubmed/27931046
http://dx.doi.org/10.1038/bjc.2016.407