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Activation of COX-2/PGE(2) Promotes Sapovirus Replication via the Inhibition of Nitric Oxide Production

Enteric caliciviruses in the genera Norovirus and Sapovirus are important pathogens that cause severe acute gastroenteritis in both humans and animals. Cyclooxygenases (COXs) and their final product, prostaglandin E(2) (PGE(2)), are known to play important roles in the modulation of both the host re...

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Detalles Bibliográficos
Autores principales: Alfajaro, Mia Madel, Choi, Jong-Soon, Kim, Deok-Song, Seo, Ja-Young, Kim, Ji-Yun, Park, Jun-Gyu, Soliman, Mahmoud, Baek, Yeong-Bin, Cho, Eun-Hyo, Kwon, Joseph, Kwon, Hyung-Jun, Park, Su-Jin, Lee, Woo Song, Kang, Mun-Il, Hosmillo, Myra, Goodfellow, Ian, Cho, Kyoung-Oh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5244346/
https://www.ncbi.nlm.nih.gov/pubmed/27881647
http://dx.doi.org/10.1128/JVI.01656-16