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Aurora Kinase A is a Biomarker for Bladder Cancer Detection and Contributes to its Aggressive Behavior

The effects of AURKA overexpression associated with poor clinical outcomes have been attributed to increased cell cycle progression and the development of genomic instability with aneuploidy. We used RNA interference to examine the effects of AURKA overexpression in human bladder cancer cells. Knock...

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Detalles Bibliográficos
Autores principales: Mobley, Aaron, Zhang, Shizhen, Bondaruk, Jolanta, Wang, Yan, Majewski, Tadeusz, Caraway, Nancy P., Huang, Li, Shoshan, Einav, Velazquez-Torres, Guermarie, Nitti, Giovanni, Lee, Sangkyou, Lee, June Goo, Fuentes-Mattei, Enrique, Willis, Daniel, Zhang, Li, Guo, Charles C., Yao, Hui, Baggerly, Keith, Lotan, Yair, Lerner, Seth P., Dinney, Colin, McConkey, David, Bar-Eli, Menashe, Czerniak, Bogdan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5244380/
https://www.ncbi.nlm.nih.gov/pubmed/28102366
http://dx.doi.org/10.1038/srep40714