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Interspecies cathelicidin comparison reveals divergence in antimicrobial activity, TLR modulation, chemokine induction and regulation of phagocytosis

Cathelicidins are short cationic peptides initially described as antimicrobial peptides, which can also modulate the immune system. Because most findings have been described in the context of human LL-37 or murine CRAMP, or have been investigated under varying conditions, it is unclear which functio...

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Detalles Bibliográficos
Autores principales: Coorens, Maarten, Scheenstra, Maaike R., Veldhuizen, Edwin J. A., Haagsman, Henk P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5244392/
https://www.ncbi.nlm.nih.gov/pubmed/28102367
http://dx.doi.org/10.1038/srep40874