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The prevalence of CTNNB1 mutations in primary aldosteronism and consequences for clinical outcomes

Constitutive activation of the Wnt pathway/β-catenin signaling may be important in aldosterone-producing adenoma (APA). However, significant gaps remain in our understanding of the prevalence and clinical outcomes after adrenalectomy in APA patients harboring CTNNB1 mutations. The molecular expressi...

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Detalles Bibliográficos
Autores principales: Wu, Vin-Cent, Wang, Shuo-Meng, Chueh, Shih-Chieh Jeff, Yang, Shao-Yu, Huang, Kuo-How, Lin, Yen-Hung, Wang, Jian-Jhong, Connolly, Rory, Hu, Ya-Hui, Gomez-Sanchez, Celso E., Peng, Kang-Yung, Wu, Kwan-Dun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5244399/
https://www.ncbi.nlm.nih.gov/pubmed/28102204
http://dx.doi.org/10.1038/srep39121