Coordinated cell motility is regulated by a combination of LKB1 farnesylation and kinase activity

Cell motility requires the precise coordination of cell polarization, lamellipodia formation, adhesion, and force generation. LKB1 is a multi-functional serine/threonine kinase that associates with actin at the cellular leading edge of motile cells and suppresses FAK. We sought to understand how LKB...

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Detalles Bibliográficos
Autores principales: Wilkinson, S., Hou, Y., Zoine, J. T., Saltz, J., Zhang, C., Chen, Z., Cooper, L. A. D., Marcus, A. I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5244416/
https://www.ncbi.nlm.nih.gov/pubmed/28102310
http://dx.doi.org/10.1038/srep40929

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5244416/
https://www.ncbi.nlm.nih.gov/pubmed/28102310
http://dx.doi.org/10.1038/srep40929

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