Cargando…

Modification of distinct ion channels differentially modulates Ca(2+) dynamics in primary cultured rat ventricular cardiomyocytes

Primary cultured cardiomyocytes show spontaneous Ca(2+) oscillations (SCOs) which not only govern contractile events, but undergo derangements that promote arrhythmogenesis through Ca(2+) -dependent mechanism. We systematically examined influence on SCOs of an array of ion channel modifiers by recor...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Xichun, Shen, Liping, Zhao, Fang, Zou, Xiaohan, He, Yuwei, Zhang, Fan, Zhang, Chunlei, Yu, Boyang, Cao, Zhengyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5244425/
https://www.ncbi.nlm.nih.gov/pubmed/28102360
http://dx.doi.org/10.1038/srep40952