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Modification of distinct ion channels differentially modulates Ca(2+) dynamics in primary cultured rat ventricular cardiomyocytes
Primary cultured cardiomyocytes show spontaneous Ca(2+) oscillations (SCOs) which not only govern contractile events, but undergo derangements that promote arrhythmogenesis through Ca(2+) -dependent mechanism. We systematically examined influence on SCOs of an array of ion channel modifiers by recor...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5244425/ https://www.ncbi.nlm.nih.gov/pubmed/28102360 http://dx.doi.org/10.1038/srep40952 |