Transcriptomic signatures differentiate survival from fatal outcomes in humans infected with Ebola virus

BACKGROUND: In 2014, Western Africa experienced an unanticipated explosion of Ebola virus infections. What distinguishes fatal from non-fatal outcomes remains largely unknown, yet is key to optimising personalised treatment strategies. We used transcriptome data for peripheral blood taken from infec...

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Detalles Bibliográficos
Autores principales: Liu, Xuan, Speranza, Emily, Muñoz-Fontela, César, Haldenby, Sam, Rickett, Natasha Y., Garcia-Dorival, Isabel, Fang, Yongxiang, Hall, Yper, Zekeng, Elsa-Gayle, Lüdtke, Anja, Xia, Dong, Kerber, Romy, Krumkamp, Ralf, Duraffour, Sophie, Sissoko, Daouda, Kenny, John, Rockliffe, Nichola, Williamson, E. Diane, Laws, Thomas R., N’Faly, Magassouba, Matthews, David A., Günther, Stephan, Cossins, Andrew R., Sprecher, Armand, Connor, John H., Carroll, Miles W., Hiscox, Julian A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5244546/
https://www.ncbi.nlm.nih.gov/pubmed/28100256
http://dx.doi.org/10.1186/s13059-016-1137-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5244546/
https://www.ncbi.nlm.nih.gov/pubmed/28100256
http://dx.doi.org/10.1186/s13059-016-1137-3

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