Unraveling the regulation of mTORC2 using logical modeling

BACKGROUND: The mammalian target of rapamycin (mTOR) is a regulator of cell proliferation, cell growth and apoptosis working through two distinct complexes: mTORC1 and mTORC2. Although much is known about the activation and inactivation of mTORC1, the processes controlling mTORC2 remain poorly chara...

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Detalles Bibliográficos
Autores principales: Thobe, Kirsten, Sers, Christine, Siebert, Heike
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5244562/
https://www.ncbi.nlm.nih.gov/pubmed/28103956
http://dx.doi.org/10.1186/s12964-016-0159-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5244562/
https://www.ncbi.nlm.nih.gov/pubmed/28103956
http://dx.doi.org/10.1186/s12964-016-0159-5

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