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Unraveling the regulation of mTORC2 using logical modeling
BACKGROUND: The mammalian target of rapamycin (mTOR) is a regulator of cell proliferation, cell growth and apoptosis working through two distinct complexes: mTORC1 and mTORC2. Although much is known about the activation and inactivation of mTORC1, the processes controlling mTORC2 remain poorly chara...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5244562/ https://www.ncbi.nlm.nih.gov/pubmed/28103956 http://dx.doi.org/10.1186/s12964-016-0159-5 |