T-cadherin deficiency increases vascular vulnerability in T2DM through impaired NO bioactivity

BACKGROUND: Endothelial dysfunction plays a critical role in the development of type 2 diabetes (T2DM). T-cadherin (T-cad) has gained recognition as a regulator of endothelial cell (EC) function. The present study examined whether T-cad deficiency increases vascular vulnerability in T2DM. METHODS: V...

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Detalles Bibliográficos
Autores principales: Wang, Han, Tao, Ling, Ambrosio, Anastasia, Yan, Wenjun, Summer, Ross, Lau, Wayne Bond, Wang, Yajing, Ma, Xinliang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Original Investigation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5244578/
https://www.ncbi.nlm.nih.gov/pubmed/28103886
http://dx.doi.org/10.1186/s12933-016-0488-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5244578/
https://www.ncbi.nlm.nih.gov/pubmed/28103886
http://dx.doi.org/10.1186/s12933-016-0488-0

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