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T-cadherin deficiency increases vascular vulnerability in T2DM through impaired NO bioactivity
BACKGROUND: Endothelial dysfunction plays a critical role in the development of type 2 diabetes (T2DM). T-cadherin (T-cad) has gained recognition as a regulator of endothelial cell (EC) function. The present study examined whether T-cad deficiency increases vascular vulnerability in T2DM. METHODS: V...
Autores principales: | Wang, Han, Tao, Ling, Ambrosio, Anastasia, Yan, Wenjun, Summer, Ross, Lau, Wayne Bond, Wang, Yajing, Ma, Xinliang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5244578/ https://www.ncbi.nlm.nih.gov/pubmed/28103886 http://dx.doi.org/10.1186/s12933-016-0488-0 |
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