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Immune-enrichment of insulin in bio-fluids on gold-nanoparticle decorated target plate and in situ detection by MALDI MS

BACKGROUND: Detection of low-abundance biomarkers using mass spectrometry (MS) is often hampered by non-target molecules in biological fluids. In addition, current procedures for sample preparation increase sample consumption and limit analysis throughput. Here, a simple strategy is proposed to cons...

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Detalles Bibliográficos
Autores principales: Liang, Kai, Wu, Hongmei, Li, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5244591/
https://www.ncbi.nlm.nih.gov/pubmed/28115918
http://dx.doi.org/10.1186/s12014-017-9139-z