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Genetic variation in the miR‐708 gene and its binding targets in bipolar disorder

OBJECTIVE: rs12576775 was found to be associated with bipolar disorder (BD) in a genome‐wide association study (GWAS). The GWAS signal implicates genes for the microRNAs miR‐708 and miR‐5579 and the first exon of the Odd Oz/ten‐m homolog 4 gene (ODZ4). In the present study, miR‐708, its surrounding...

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Detalles Bibliográficos
Autores principales: Fiorentino, Alessia, O'Brien, Niamh Louise, Sharp, Sally Isabel, Curtis, David, Bass, Nicholas James, McQuillin, Andrew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5244671/
https://www.ncbi.nlm.nih.gov/pubmed/27864917
http://dx.doi.org/10.1111/bdi.12448