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Factorial versus multi‐arm multi‐stage designs for clinical trials with multiple treatments
When several treatments are available for evaluation in a clinical trial, different design options are available. We compare multi‐arm multi‐stage with factorial designs, and in particular, we will consider a 2 × 2 factorial design, where groups of patients will either take treatments A, B, both or...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley & Sons, Ltd
2016
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5244690/ https://www.ncbi.nlm.nih.gov/pubmed/27804166 http://dx.doi.org/10.1002/sim.7159 |