Evolutionary relationships of Aurora kinases: Implications for model organism studies and the development of anti-cancer drugs

BACKGROUND: As key regulators of mitotic chromosome segregation, the Aurora family of serine/threonine kinases play an important role in cell division. Abnormalities in Aurora kinases have been strongly linked with cancer, which has lead to the recent development of new classes of anti-cancer drugs...

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Detalles Bibliográficos
Autores principales: Brown, James R, Koretke, Kristin K, Birkeland, Marian L, Sanseau, Philippe, Patrick, Denis R
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2004
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC524484/
https://www.ncbi.nlm.nih.gov/pubmed/15476560
http://dx.doi.org/10.1186/1471-2148-4-39

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC524484/
https://www.ncbi.nlm.nih.gov/pubmed/15476560
http://dx.doi.org/10.1186/1471-2148-4-39

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