Cargando…
Evolutionary relationships of Aurora kinases: Implications for model organism studies and the development of anti-cancer drugs
BACKGROUND: As key regulators of mitotic chromosome segregation, the Aurora family of serine/threonine kinases play an important role in cell division. Abnormalities in Aurora kinases have been strongly linked with cancer, which has lead to the recent development of new classes of anti-cancer drugs...
| Autores principales: | , , , , |
|---|---|
| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2004
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC524484/ https://www.ncbi.nlm.nih.gov/pubmed/15476560 http://dx.doi.org/10.1186/1471-2148-4-39 |