Cargando…

Inhibition of the CyclinD1 promoter in response to sonic hedgehog signaling pathway transduction is mediated by Gli1

Medulloblastoma (MB) is the most common malignant tumor of the central nervous system in children. Accumulating evidence suggests a major role for the activation of the sonic hedgehog (SHH) signaling pathway in the development of MB cells; however, the mechanisms underlying the effect of this pathwa...

Descripción completa

Detalles Bibliográficos
Autores principales: Lin, Zhongxiao, Sheng, Hansong, You, Chaoguo, Cai, Ming, Zhang, Yiping, Yu, Li Sheng, Yu, Xiaoming, Lin, Jian, Zhang, Nu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5244851/
https://www.ncbi.nlm.nih.gov/pubmed/28123507
http://dx.doi.org/10.3892/etm.2016.3969