Identification of compounds with anti-human cytomegalovirus activity that inhibit production of IE2 proteins

Using a high throughput screening methodology we surveyed a collection of largely uncharacterized validated or suspected kinase inhibitors for anti-human cytomegalovirus (HCMV) activity. From this screen we identified three structurally related 5-aminopyrazine compounds (XMD7-1, -2 and -27) that inh...

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Detalles Bibliográficos
Autores principales: Beelontally, Rooksarr, Wilkie, Gavin S., Lau, Betty, Goodmaker, Charles J., Ho, Catherine M.K., Swanson, Chad M., Deng, Xianming, Wang, Jinhua, Gray, Nathanael S., Davison, Andrew J., Strang, Blair L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5244968/
https://www.ncbi.nlm.nih.gov/pubmed/27956134
http://dx.doi.org/10.1016/j.antiviral.2016.12.006

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5244968/
https://www.ncbi.nlm.nih.gov/pubmed/27956134
http://dx.doi.org/10.1016/j.antiviral.2016.12.006

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