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MicroRNA-101 suppresses progression of lung cancer through the PTEN/AKT signaling pathway by targeting DNA methyltransferase 3A

It is well established that transcriptional silencing of critical tumor suppressor genes by DNA methylation is a fundamental process in the initiation of lung cancer. However, the involvement of microRNAs (miRNAs) in restoring abnormal DNA methylation patterns in lung cancer is not well understood....

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Detalles Bibliográficos
Autores principales: Wang, Lumin, Yao, Jiayi, Sun, Hongfei, He, Kang, Tong, Dongdong, Song, Tusheng, Huang, Chen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5245075/
https://www.ncbi.nlm.nih.gov/pubmed/28123563
http://dx.doi.org/10.3892/ol.2016.5423