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The connection domain in reverse transcriptase facilitates the in vivo annealing of tRNA(Lys3 )to HIV-1 genomic RNA

The primer tRNA for reverse transcription in HIV-1, tRNA(Lys3), is selectively packaged into the virus during its assembly, and annealed to the viral genomic RNA. The ribonucleoprotein complex that is involved in the packaging and annealing of tRNA(Lys )into HIV-1 consists of Gag, GagPol, tRNA(Lys),...

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Detalles Bibliográficos
Autores principales: Cen, Shan, Niu, Meijuan, Kleiman, Lawrence
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC524520/
https://www.ncbi.nlm.nih.gov/pubmed/15494076
http://dx.doi.org/10.1186/1742-4690-1-33