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The connection domain in reverse transcriptase facilitates the in vivo annealing of tRNA(Lys3 )to HIV-1 genomic RNA
The primer tRNA for reverse transcription in HIV-1, tRNA(Lys3), is selectively packaged into the virus during its assembly, and annealed to the viral genomic RNA. The ribonucleoprotein complex that is involved in the packaging and annealing of tRNA(Lys )into HIV-1 consists of Gag, GagPol, tRNA(Lys),...
Autores principales: | Cen, Shan, Niu, Meijuan, Kleiman, Lawrence |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2004
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC524520/ https://www.ncbi.nlm.nih.gov/pubmed/15494076 http://dx.doi.org/10.1186/1742-4690-1-33 |
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