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Genetically Thermo-Stabilised, Immunogenic Poliovirus Empty Capsids; a Strategy for Non-replicating Vaccines

While wild type polio has been nearly eradicated there will be a need to continue immunisation programmes for some time because of the possibility of re-emergence and the existence of long term excreters of poliovirus. All vaccines in current use depend on growth of virus and most of the non-replica...

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Detalles Bibliográficos
Autores principales: Fox, Helen, Knowlson, Sarah, Minor, Philip D., Macadam, Andrew J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5245777/
https://www.ncbi.nlm.nih.gov/pubmed/28103317
http://dx.doi.org/10.1371/journal.ppat.1006117