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Aristaless Related Homeobox (ARX) Interacts with β-Catenin, BCL9, and P300 to Regulate Canonical Wnt Signaling

Mutations in the Aristaless Related Homeobox (ARX) gene are associated with a spectrum of structural (lissencephaly) and functional (epilepsy and intellectual disabilities) neurodevelopmental disorders. How mutations in this single transcription factor can result in such a broad range of phenotypes...

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Detalles Bibliográficos
Autores principales: Cho, Il-Taeg, Lim, Youngshin, Golden, Jeffrey A., Cho, Ginam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5245867/
https://www.ncbi.nlm.nih.gov/pubmed/28103279
http://dx.doi.org/10.1371/journal.pone.0170282