Radioiodinated Exendin-4 Is Superior to the Radiometal-Labelled Glucagon-Like Peptide-1 Receptor Probes Overcoming Their High Kidney Uptake

GLP-1 receptors are ideal targets for preoperative imaging of benign insulinoma and for quantifying the beta cell mass. The existing clinical tracers targeting GLP-1R are all agonists with low specific activity and very high kidney uptake. In order to solve those issues we evaluated GLP-1R agonist E...

Descripción completa

Detalles Bibliográficos
Autores principales: Läppchen, Tilman, Tönnesmann, Roswitha, Eersels, Jos, Meyer, Philipp T., Maecke, Helmut R., Rylova, Svetlana N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5245897/
https://www.ncbi.nlm.nih.gov/pubmed/28103285
http://dx.doi.org/10.1371/journal.pone.0170435

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5245897/
https://www.ncbi.nlm.nih.gov/pubmed/28103285
http://dx.doi.org/10.1371/journal.pone.0170435

Ejemplares similares