TRIM25 Enhances the Antiviral Action of Zinc-Finger Antiviral Protein (ZAP)

The host factor and interferon (IFN)-stimulated gene (ISG) product, zinc-finger antiviral protein (ZAP), inhibits a number of diverse viruses by usurping and intersecting with multiple cellular pathways. To elucidate its antiviral mechanism, we perform a loss-of-function genome-wide RNAi screen to i...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Melody M. H., Lau, Zerlina, Cheung, Pamela, Aguilar, Eduardo G., Schneider, William M., Bozzacco, Leonia, Molina, Henrik, Buehler, Eugen, Takaoka, Akinori, Rice, Charles M., Felsenfeld, Dan P., MacDonald, Margaret R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5245905/
https://www.ncbi.nlm.nih.gov/pubmed/28060952
http://dx.doi.org/10.1371/journal.ppat.1006145

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5245905/
https://www.ncbi.nlm.nih.gov/pubmed/28060952
http://dx.doi.org/10.1371/journal.ppat.1006145

Ejemplares similares