Cargando…
TRIM25 Enhances the Antiviral Action of Zinc-Finger Antiviral Protein (ZAP)
The host factor and interferon (IFN)-stimulated gene (ISG) product, zinc-finger antiviral protein (ZAP), inhibits a number of diverse viruses by usurping and intersecting with multiple cellular pathways. To elucidate its antiviral mechanism, we perform a loss-of-function genome-wide RNAi screen to i...
Autores principales: | Li, Melody M. H., Lau, Zerlina, Cheung, Pamela, Aguilar, Eduardo G., Schneider, William M., Bozzacco, Leonia, Molina, Henrik, Buehler, Eugen, Takaoka, Akinori, Rice, Charles M., Felsenfeld, Dan P., MacDonald, Margaret R. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5245905/ https://www.ncbi.nlm.nih.gov/pubmed/28060952 http://dx.doi.org/10.1371/journal.ppat.1006145 |
Ejemplares similares
-
The Zinc-Finger Antiviral Protein ZAP Inhibits LINE and Alu Retrotransposition
por: Moldovan, John B., et al.
Publicado: (2015) -
Does the Zinc Finger Antiviral Protein (ZAP) Shape the Evolution of Herpesvirus Genomes?
por: Lin, Yao-Tang, et al.
Publicado: (2021) -
ZAP’s stress granule localization is correlated with its antiviral activity and induced by virus replication
por: Law, Lok Man John, et al.
Publicado: (2019) -
Alphavirus Evasion of Zinc Finger Antiviral Protein (ZAP) Correlates with CpG Suppression in a Specific Viral nsP2 Gene Sequence
por: Nguyen, LeAnn P., et al.
Publicado: (2023) -
KHNYN is essential for the zinc finger antiviral protein (ZAP) to restrict HIV-1 containing clustered CpG dinucleotides
por: Ficarelli, Mattia, et al.
Publicado: (2019)