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Liposomes derivatized with multimeric copies of KCCYSL peptide as targeting agents for HER-2-overexpressing tumor cells

Mixed liposomes, obtained by coaggregation of 1,2-dioleoyl-sn-glycero-3-phosphocholine and of the synthetic monomer containing a gadolinium complex ([C18](2)DTPA[Gd]) have been prepared. Liposomes externally decorated with KCCYSL (P6.1 peptide) sequence in its monomeric, dimeric, and tetrameric form...

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Detalles Bibliográficos
Autores principales: Ringhieri, Paola, Mannucci, Silvia, Conti, Giamaica, Nicolato, Elena, Fracasso, Giulio, Marzola, Pasquina, Morelli, Giancarlo, Accardo, Antonella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5245980/
https://www.ncbi.nlm.nih.gov/pubmed/28144135
http://dx.doi.org/10.2147/IJN.S113607