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Liposomes derivatized with multimeric copies of KCCYSL peptide as targeting agents for HER-2-overexpressing tumor cells
Mixed liposomes, obtained by coaggregation of 1,2-dioleoyl-sn-glycero-3-phosphocholine and of the synthetic monomer containing a gadolinium complex ([C18](2)DTPA[Gd]) have been prepared. Liposomes externally decorated with KCCYSL (P6.1 peptide) sequence in its monomeric, dimeric, and tetrameric form...
Autores principales: | Ringhieri, Paola, Mannucci, Silvia, Conti, Giamaica, Nicolato, Elena, Fracasso, Giulio, Marzola, Pasquina, Morelli, Giancarlo, Accardo, Antonella |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5245980/ https://www.ncbi.nlm.nih.gov/pubmed/28144135 http://dx.doi.org/10.2147/IJN.S113607 |
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