Plaque-hyaluronidase-responsive high-density-lipoprotein-mimetic nanoparticles for multistage intimal-macrophage-targeted drug delivery and enhanced anti-atherosclerotic therapy

Increasing evidence has highlighted the pivotal role that intimal macrophage (iMΦ) plays in the pathophysiology of atherosclerotic plaques, which represents an attractive target for atherosclerosis treatment. In this work, to address the insufficient specificity of conventional reconstituted high-de...

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Detalles Bibliográficos
Autores principales: Zhang, Mengyuan, He, Jianhua, Jiang, Cuiping, Zhang, Wenli, Yang, Yun, Wang, Zhiyu, Liu, Jianping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2017
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5245982/
https://www.ncbi.nlm.nih.gov/pubmed/28144137
http://dx.doi.org/10.2147/IJN.S124252

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5245982/
https://www.ncbi.nlm.nih.gov/pubmed/28144137
http://dx.doi.org/10.2147/IJN.S124252

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