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Circadian Neuron Feedback Controls the Drosophila Sleep-Activity Profile

Little is known about the ability of Drosophila circadian neurons to promote sleep. We show here with optogenetic manipulations and video recording that a subset of dorsal clock neurons (DN1s) are potent sleep-promoting cells, releasing glutamate to directly inhibit key pacemaker neurons. These pace...

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Detalles Bibliográficos
Autores principales: Guo, Fang, Yu, Junwei, Jung, Hyung Jae, Abruzzi, Katharine C., Luo, Weifei, Griffith, Leslie C., Rosbash, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5247284/
https://www.ncbi.nlm.nih.gov/pubmed/27479324
http://dx.doi.org/10.1038/nature19097