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Neuroprotective action of N-acetyl serotonin in oxidative stress-induced apoptosis through the activation of both TrkB/CREB/BDNF pathway and Akt/Nrf2/Antioxidant enzyme in neuronal cells

N-acetyl serotonin (NAS) as a melatonin precursor has neuroprotective actions. Nonetheless, it is not clarified how NAS protects neuronal cells against oxidative stress. Recently, we have reported that N-palmitoyl serotonins possessed properties of antioxidants and neuroprotection. Based on those, w...

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Detalles Bibliográficos
Autores principales: Yoo, Jae-Myung, Lee, Bo Dam, Sok, Dai-Eun, Ma, Jin Yuel, Kim, Mee Ree
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5247570/
https://www.ncbi.nlm.nih.gov/pubmed/28110215
http://dx.doi.org/10.1016/j.redox.2016.12.034