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GLP-1R Signaling Directly Activates Arcuate Nucleus Kisspeptin Action in Brain Slices but Does not Rescue Luteinizing Hormone Inhibition in Ovariectomized Mice During Negative Energy Balance
Kisspeptin (Kiss1) neurons in the hypothalamic arcuate nucleus (ARC) are key components of the hypothalamic-pituitary-gonadal axis, as they regulate the basal pulsatile release of gonadotropin releasing hormone (GnRH). ARC Kiss1 action is dependent on energy status, and unmasking metabolic factors r...
Autores principales: | Heppner, Kristy M., Baquero, Arian F., Bennett, Camdin M., Lindsley, Sarah R., Kirigiti, Melissa A., Bennett, Baylin, Bosch, Martha A., Mercer, Aaron J., Rønnekleiv, Oline K., True, Cadence, Grove, Kevin L., Smith, M. Susan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Society for Neuroscience
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5247618/ https://www.ncbi.nlm.nih.gov/pubmed/28144621 http://dx.doi.org/10.1523/ENEURO.0198-16.2016 |
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