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LanCL proteins are not Involved in Lanthionine Synthesis in Mammals

LanC-like (LanCL) proteins are mammalian homologs of bacterial LanC enzymes, which catalyze the addition of the thiol of Cys to dehydrated Ser residues during the biosynthesis of lanthipeptides, a class of natural products formed by post-translational modification of precursor peptides. The function...

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Detalles Bibliográficos
Autores principales: He, Chang, Zeng, Min, Dutta, Debapriya, Koh, Tong Hee, Chen, Jie, van der Donk, Wilfred A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5247676/
https://www.ncbi.nlm.nih.gov/pubmed/28106097
http://dx.doi.org/10.1038/srep40980