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Early Secreted Antigenic Target of 6-kDa of Mycobacterium tuberculosis Stimulates IL-6 Production by Macrophages through Activation of STAT3

As early secreted antigenic target of 6 kDa (ESAT-6) of Mycobacterium tuberculosis (Mtb) is an essential virulence factor and macrophages are critical for tuberculosis infection and immunity, we studied ESAT-6 stimulated IL-6 production by macrophages. ESAT-6 stimulated significantly higher IL-6 sec...

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Detalles Bibliográficos
Autores principales: Jung, Bock-Gie, Wang, Xisheng, Yi, Na, Ma, Justin, Turner, Joanne, Samten, Buka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5247711/
https://www.ncbi.nlm.nih.gov/pubmed/28106119
http://dx.doi.org/10.1038/srep40984