Cargando…
Endoplasmic Reticulum Oxidative Stress Triggers Tgf-Beta-Dependent Muscle Dysfunction by Accelerating Ascorbic Acid Turnover
Endoplasmic reticulum (ER) and oxidative stress are two related phenomena that have important metabolic consequences. As many skeletal muscle diseases are triggered by oxidative stress, we explored the chain of events linking a hyperoxidized ER (which causes ER and oxidative stress) with skeletal mu...
Autores principales: | Pozzer, Diego, Favellato, Mariagrazia, Bolis, Marco, Invernizzi, Roberto William, Solagna, Francesca, Blaauw, Bert, Zito, Ester |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5247721/ https://www.ncbi.nlm.nih.gov/pubmed/28106121 http://dx.doi.org/10.1038/srep40993 |
Ejemplares similares
-
Endoplasmic Reticulum Thiol Oxidase Deficiency Leads to Ascorbic Acid Depletion and Noncanonical Scurvy in Mice
por: Zito, Ester, et al.
Publicado: (2012) -
Processing and turnover of the Hedgehog protein in the endoplasmic reticulum
por: Chen, Xin, et al.
Publicado: (2011) -
Endoplasmic reticulum oxidoreductin 1‐alpha deficiency and activation of protein translation synergistically impair breast tumour resilience
por: Varone, Ersilia, et al.
Publicado: (2022) -
A maladaptive ER stress response triggers dysfunction in highly active muscles of mice with SELENON loss
por: Pozzer, Diego, et al.
Publicado: (2018) -
Defective endoplasmic reticulum-mitochondria contacts and bioenergetics in SEPN1-related myopathy
por: Filipe, Anne, et al.
Publicado: (2020)