Norovirus P particle-based active Aβ immunotherapy elicits sufficient immunogenicity and improves cognitive capacity in a mouse model of Alzheimer’s disease

Disease-modifying immunotherapies focusing on reducing amyloid-beta (Aβ) deposition are the main treatment for Alzheimer’s disease (AD). However, none of the Aβ immunotherapies has produced clinically meaningful results to date. The main reason for this lack of efficacy is that the vaccine induces i...

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Detalles Bibliográficos
Autores principales: Fu, Lu, Li, Yingnan, Hu, Yue, Zheng, Yayuan, Yu, Bin, Zhang, Haihong, Wu, Jiaxin, Wu, Hui, Yu, Xianghui, Kong, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5247735/
https://www.ncbi.nlm.nih.gov/pubmed/28106117
http://dx.doi.org/10.1038/srep41041

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5247735/
https://www.ncbi.nlm.nih.gov/pubmed/28106117
http://dx.doi.org/10.1038/srep41041

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