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Identification of LukPQ, a novel, equid-adapted leukocidin of Staphylococcus aureus

Bicomponent pore-forming leukocidins are a family of potent toxins secreted by Staphylococcus aureus, which target white blood cells preferentially and consist of an S- and an F-component. The S-component recognizes a receptor on the host cell, enabling high-affinity binding to the cell surface, aft...

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Detalles Bibliográficos
Autores principales: Koop, Gerrit, Vrieling, Manouk, Storisteanu, Daniel M. L., Lok, Laurence S. C., Monie, Tom, van Wigcheren, Glenn, Raisen, Claire, Ba, Xiaoliang, Gleadall, Nicholas, Hadjirin, Nazreen, Timmerman, Arjen J., Wagenaar, Jaap A., Klunder, Heleen M., Fitzgerald, J. Ross, Zadoks, Ruth, Paterson, Gavin K., Torres, Carmen, Waller, Andrew S., Loeffler, Anette, Loncaric, Igor, Hoet, Armando E., Bergström, Karin, De Martino, Luisa, Pomba, Constança, de Lencastre, Hermínia, Ben Slama, Karim, Gharsa, Haythem, Richardson, Emily J., Chilvers, Edwin R., de Haas, Carla, van Kessel, Kok, van Strijp, Jos A. G., Harrison, Ewan M., Holmes, Mark A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5247767/
https://www.ncbi.nlm.nih.gov/pubmed/28106142
http://dx.doi.org/10.1038/srep40660