Food-grade TiO(2) impairs intestinal and systemic immune homeostasis, initiates preneoplastic lesions and promotes aberrant crypt development in the rat colon

Food-grade titanium dioxide (TiO(2)) containing a nanoscale particle fraction (TiO(2)-NPs) is approved as a white pigment (E171 in Europe) in common foodstuffs, including confectionary. There are growing concerns that daily oral TiO(2)-NP intake is associated with an increased risk of chronic intest...

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Detalles Bibliográficos
Autores principales: Bettini, Sarah, Boutet-Robinet, Elisa, Cartier, Christel, Coméra, Christine, Gaultier, Eric, Dupuy, Jacques, Naud, Nathalie, Taché, Sylviane, Grysan, Patrick, Reguer, Solenn, Thieriet, Nathalie, Réfrégiers, Matthieu, Thiaudière, Dominique, Cravedi, Jean-Pierre, Carrière, Marie, Audinot, Jean-Nicolas, Pierre, Fabrice H., Guzylack-Piriou, Laurence, Houdeau, Eric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5247795/
https://www.ncbi.nlm.nih.gov/pubmed/28106049
http://dx.doi.org/10.1038/srep40373

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5247795/
https://www.ncbi.nlm.nih.gov/pubmed/28106049
http://dx.doi.org/10.1038/srep40373

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