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Food-grade TiO(2) impairs intestinal and systemic immune homeostasis, initiates preneoplastic lesions and promotes aberrant crypt development in the rat colon
Food-grade titanium dioxide (TiO(2)) containing a nanoscale particle fraction (TiO(2)-NPs) is approved as a white pigment (E171 in Europe) in common foodstuffs, including confectionary. There are growing concerns that daily oral TiO(2)-NP intake is associated with an increased risk of chronic intest...
Autores principales: | Bettini, Sarah, Boutet-Robinet, Elisa, Cartier, Christel, Coméra, Christine, Gaultier, Eric, Dupuy, Jacques, Naud, Nathalie, Taché, Sylviane, Grysan, Patrick, Reguer, Solenn, Thieriet, Nathalie, Réfrégiers, Matthieu, Thiaudière, Dominique, Cravedi, Jean-Pierre, Carrière, Marie, Audinot, Jean-Nicolas, Pierre, Fabrice H., Guzylack-Piriou, Laurence, Houdeau, Eric |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5247795/ https://www.ncbi.nlm.nih.gov/pubmed/28106049 http://dx.doi.org/10.1038/srep40373 |
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