Dietary treatment of Crohn’s disease: perceptions of families with children treated by exclusive enteral nutrition, a questionnaire survey

BACKGROUND: Diet is strongly associated with the aetiology of Crohn’s Disease (CD) and exclusive enteral nutrition (EEN) is the primary induction treatment in paediatric CD. This study explored opinions around the use of EEN and alternative novel, solid food-based diets (SFDs) expressed by paediatri...

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Autores principales: Svolos, Vaios, Gerasimidis, Konstantinos, Buchanan, Elaine, Curtis, Lee, Garrick, Vikki, Hay, Jacqueline, Laird, Susan, Munro, Joanna, Gaya, Daniel R., Russell, Richard K., Hansen, Richard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5247812/
https://www.ncbi.nlm.nih.gov/pubmed/28103809
http://dx.doi.org/10.1186/s12876-016-0564-7
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author Svolos, Vaios
Gerasimidis, Konstantinos
Buchanan, Elaine
Curtis, Lee
Garrick, Vikki
Hay, Jacqueline
Laird, Susan
Munro, Joanna
Gaya, Daniel R.
Russell, Richard K.
Hansen, Richard
author_facet Svolos, Vaios
Gerasimidis, Konstantinos
Buchanan, Elaine
Curtis, Lee
Garrick, Vikki
Hay, Jacqueline
Laird, Susan
Munro, Joanna
Gaya, Daniel R.
Russell, Richard K.
Hansen, Richard
author_sort Svolos, Vaios
collection PubMed
description BACKGROUND: Diet is strongly associated with the aetiology of Crohn’s Disease (CD) and exclusive enteral nutrition (EEN) is the primary induction treatment in paediatric CD. This study explored opinions around the use of EEN and alternative novel, solid food-based diets (SFDs) expressed by paediatric patients with CD, previously treated with EEN and their parents. METHODS: This anonymous questionnaire surveyed families of CD patients treated with EEN over 1 year. Two questionnaire forms were completed; one asking the patients’ opinions and another referring to their main carer. This questionnaire explored participants’ demographic characteristics; acceptability of a repeat EEN course to treat a future flare (EEN repeat); their opinion on how difficult EEN would be compared to an example SFD; and their intention to participate in a future clinical trial assessing the therapeutic efficacy of an SFD in CD. RESULTS: Forty-one families of CD patients were approached with 29 sending replies (71%). Most of our participants were positive on completing another EEN course, however the majority would choose an SFD alternative (Patients:66, Parents:72%). Both patients and their parents rated EEN to be more difficult to adhere to compared to an example SFD (p < 0.05), and their ratings were strongly correlated (EEN:r = 0.83, SFD:r = 0.75, p < 0.001). The majority of our respondents would agree to participate in a clinical trial assessing an SFD’s effectiveness (Patients:79, Parents:72%) for the management of active CD. CONCLUSIONS: While patients with CD and their families would accept an EEN repeat, the majority would prefer an SFD alternative. CD families surveyed are supportive of the development of solid food-based dietary treatments. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1186/s12876-016-0564-7) contains supplementary material, which is available to authorized users.
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spelling pubmed-52478122017-01-23 Dietary treatment of Crohn’s disease: perceptions of families with children treated by exclusive enteral nutrition, a questionnaire survey Svolos, Vaios Gerasimidis, Konstantinos Buchanan, Elaine Curtis, Lee Garrick, Vikki Hay, Jacqueline Laird, Susan Munro, Joanna Gaya, Daniel R. Russell, Richard K. Hansen, Richard BMC Gastroenterol Research Article BACKGROUND: Diet is strongly associated with the aetiology of Crohn’s Disease (CD) and exclusive enteral nutrition (EEN) is the primary induction treatment in paediatric CD. This study explored opinions around the use of EEN and alternative novel, solid food-based diets (SFDs) expressed by paediatric patients with CD, previously treated with EEN and their parents. METHODS: This anonymous questionnaire surveyed families of CD patients treated with EEN over 1 year. Two questionnaire forms were completed; one asking the patients’ opinions and another referring to their main carer. This questionnaire explored participants’ demographic characteristics; acceptability of a repeat EEN course to treat a future flare (EEN repeat); their opinion on how difficult EEN would be compared to an example SFD; and their intention to participate in a future clinical trial assessing the therapeutic efficacy of an SFD in CD. RESULTS: Forty-one families of CD patients were approached with 29 sending replies (71%). Most of our participants were positive on completing another EEN course, however the majority would choose an SFD alternative (Patients:66, Parents:72%). Both patients and their parents rated EEN to be more difficult to adhere to compared to an example SFD (p < 0.05), and their ratings were strongly correlated (EEN:r = 0.83, SFD:r = 0.75, p < 0.001). The majority of our respondents would agree to participate in a clinical trial assessing an SFD’s effectiveness (Patients:79, Parents:72%) for the management of active CD. CONCLUSIONS: While patients with CD and their families would accept an EEN repeat, the majority would prefer an SFD alternative. CD families surveyed are supportive of the development of solid food-based dietary treatments. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1186/s12876-016-0564-7) contains supplementary material, which is available to authorized users. BioMed Central 2017-01-19 /pmc/articles/PMC5247812/ /pubmed/28103809 http://dx.doi.org/10.1186/s12876-016-0564-7 Text en © The Author(s). 2017 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Research Article
Svolos, Vaios
Gerasimidis, Konstantinos
Buchanan, Elaine
Curtis, Lee
Garrick, Vikki
Hay, Jacqueline
Laird, Susan
Munro, Joanna
Gaya, Daniel R.
Russell, Richard K.
Hansen, Richard
Dietary treatment of Crohn’s disease: perceptions of families with children treated by exclusive enteral nutrition, a questionnaire survey
title Dietary treatment of Crohn’s disease: perceptions of families with children treated by exclusive enteral nutrition, a questionnaire survey
title_full Dietary treatment of Crohn’s disease: perceptions of families with children treated by exclusive enteral nutrition, a questionnaire survey
title_fullStr Dietary treatment of Crohn’s disease: perceptions of families with children treated by exclusive enteral nutrition, a questionnaire survey
title_full_unstemmed Dietary treatment of Crohn’s disease: perceptions of families with children treated by exclusive enteral nutrition, a questionnaire survey
title_short Dietary treatment of Crohn’s disease: perceptions of families with children treated by exclusive enteral nutrition, a questionnaire survey
title_sort dietary treatment of crohn’s disease: perceptions of families with children treated by exclusive enteral nutrition, a questionnaire survey
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5247812/
https://www.ncbi.nlm.nih.gov/pubmed/28103809
http://dx.doi.org/10.1186/s12876-016-0564-7
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