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Sinularin induces DNA damage, G2/M phase arrest, and apoptosis in human hepatocellular carcinoma cells

BACKGROUND: Sinularin isolated from the cultured soft coral Sinularia flexibilis has been reported to exert potent cytotoxic effects against particular types of cancer. This study was carried out to investigate the cytotoxic effects in sinularin-treated human hepatocellular carcinoma cells, HepG2, a...

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Detalles Bibliográficos
Autores principales: Chung, Ting-Wen, Lin, Shih-Chao, Su, Jui-Hsin, Chen, Yu-Kuo, Lin, Chi-Chien, Chan, Hong-Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5248443/
https://www.ncbi.nlm.nih.gov/pubmed/28103869
http://dx.doi.org/10.1186/s12906-017-1583-9