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TIM-1 defines a human regulatory B cell population that is altered in frequency and function in systemic sclerosis patients

BACKGROUND: Systemic sclerosis (SSc) is a systemic autoimmune disease characterized by excessive production of extracellular matrix by fibroblasts on skin and internal organs. Although Th2 cells have been involved in fibroblast stimulation, hyperactivated B cells may also play an important role. Reg...

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Detalles Bibliográficos
Autores principales: Aravena, Octavio, Ferrier, Ashley, Menon, Madhvi, Mauri, Claudia, Aguillón, Juan Carlos, Soto, Lilian, Catalán, Diego
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5248463/
https://www.ncbi.nlm.nih.gov/pubmed/28103916
http://dx.doi.org/10.1186/s13075-016-1213-9