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TIM-1 defines a human regulatory B cell population that is altered in frequency and function in systemic sclerosis patients
BACKGROUND: Systemic sclerosis (SSc) is a systemic autoimmune disease characterized by excessive production of extracellular matrix by fibroblasts on skin and internal organs. Although Th2 cells have been involved in fibroblast stimulation, hyperactivated B cells may also play an important role. Reg...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5248463/ https://www.ncbi.nlm.nih.gov/pubmed/28103916 http://dx.doi.org/10.1186/s13075-016-1213-9 |