Cargando…

Stepwise addition of genetic changes correlated with histological change from “well-differentiated” to “sarcomatoid” phenotypes: a case report

BACKGROUND: Sarcomatoid cancer is defined by the World Health Organization as a category of non-small cell lung cancers with sarcoma or sarcoma-like differentiation. They are characterized by poor prognosis and resistance to conventional chemotherapy. However, the mutational profile of sarcomatoid c...

Descripción completa

Detalles Bibliográficos
Autores principales: Goto, Taichiro, Hirotsu, Yosuke, Mochizuki, Hitoshi, Nakagomi, Takahiro, Oyama, Toshio, Amemiya, Kenji, Omata, Masao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5248474/
https://www.ncbi.nlm.nih.gov/pubmed/28103823
http://dx.doi.org/10.1186/s12885-017-3059-1